News | Leadsynbio's fermentation-produced NMN achieves Self-GRAS status, securing compliant access to the U.S. market

Recently, Leadsynbio’s microbial-fermentation-produced NMN (β-nicotinamide mononucleotide) has officially passed the authentication of U.S. Self-GRAS. This signifies that our NMN can be sold and used as a safe and compliant food ingredient in the U.S. market, providing crucial support for Leadsynbio’s global expansion.

GRAS (Generally Recognized as Safe) is a core evaluation system under the U.S. food regulatory framework for determining the safety attributes of food ingredients. The certification confirms that our fermentation-based NMN has received formal recognition from the authoritative expert panel regarding its safety, qualifying it for compliant supply to the U.S. market as both a food ingredient and food additive. According to publicly available information, Leadsynbio is one of the earliest companies in China to industrialize NMN using microbial fermentation technology and obtain Self-GRAS certification.

Compared to traditional processes, Leadsynbio’s fermentation approach offers significant advantages in green and safe raw material sources, mild production conditions, and high product purity. We have already achieved hundred-ton-scale production, possessing stable large-scale supply capabilities. According to data from China lnsights Consultancy (CIC) , Leadsynbio ranks among the world’s leading NMN raw material suppliers. Together with multiple international certifications such as KOSHER and HALAL, the Self-GRAS achievement further strengthens the global compliance foundation and overall competitiveness of our NMN. With continuous process optimization and further capacity expansion, our industrial advantages in the NMN raw material market are expected to be consolidated and enhanced.